Recombinant Human Interleukin-35/IL-35,BR

Known as:Interleukin 35; IL35; hIL35
Derived from:Human cells
Purity:Greater than 80% as determined by reducing SDS-PAGE.
Formulation:Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Shipping:The product is shipped at ambient temperature.
Storage:Lyophilized protein should be stored at < -20°c,="" though="" stable="" at="" room="" temperature="" for="" 3="" weeks.reconstituted="" protein="" solution="" can="" be="" stored="" at="" 4-7°c="" for="" 2-7="" days.aliquots="" of="" reconstituted="" samples="" are="" stable="" at="">< -20°c="" for="" 3="">
Reconstitution:Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Endotoxin:Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Background:Interleukin-35 is a newest and potent suppressive cytokine of the IL-12 family. Unlike other members of the IL-12 family which are produced mainly by antigen-presenting cells (APCs), IL-35 has been identified as a potentially immunosuppressive cytokine primarily produced by regulatory T (Treg) cells, and to a lesser extent by activated dendritic cells and macrophages. IL-35 is composed of the IL-12 p35 subunit and the IL-27 Epstein–Barr virus-induced protein 3 (EBI3) subunit. IL-35 plays an important role in many disease models and has been recently shown to have additional functions aside from inhibition of proliferation, including inducing its own expression in non-Treg cells.
规格:10ug, 50ug, 500ug, 1mg, Recombinant Human Interleukin-35 is produced by our Mammalian expression system and the target gene encoding Arg21-Lys229&Arg23-Ser219 is expressed with a Fc tag at the C-terminus.注意：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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