Anti-MDM2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-MDM2 Polyclonal Antibody
中文名称： 双微体2癌基因抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse
应用： IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-200.

抗体信息

靶标： MDM2
别名： MDM2 (phospho T218), MDM2 (phospho Thr218), p-MDM2 (T218), p-MDM2 (Thr218), Double minute 2 protein, Hdm 2, HDM2, MDM 2, Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104kDa, MDM2BP, Mouse Double Minute 2, MTBP, Murine Double Minute Chromosome 2, Oncoprotein Mdm2, p53 Binding Protein Mdm2, Ubiquitin protein ligase E3 Mdm2, MDM2_HUMAN, E3 ubiquitin-protein ligase Mdm2
背景说明： This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
Swiss Prot： Q00987
Gene ID： 4193
亚细胞定位： Cytoplasm Nucleus nucleolus nucleoplasm
免疫原： A synthetic peptide of human MDM2
Public Immunogen Range： 231-330aa
理论分子量： 55kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.03% Proclin300，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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