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- Anti-FGR Polyclonal Antibody,BR
Anti-FGR Polyclonal Antibody,BR
Anti-FGR Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-FGR Polyclonal Antibody中文名称: 原癌基因c FGR抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Mouse ; Human
应用: IHC ; WB
稀释比例: WB 1:500-2000. IHC 1:50-200.
抗体信息
靶标: FGR别名: c fgr, c fgr protooncogene, c src 2 proto oncogene, c src2, Fgr, FGR_HUMAN, FLJ43153, Gardner Rasheed feline sarcoma viral (v fgr), Gardner Rasheed feline sarcoma viral (v fgr) oncogene homolog, Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, MGC75096, p55 c fgr protein, P55 FGR, P55-FGR, p55c fgr, p58-Fgr, p58c fgr, p58c-Fgr, Proto oncogene c Fgr, Proto oncogene tyrosine protein kinase FGR, Proto-oncogene c-Fgr, SRC 2, SRC2, Tyrosine protein kinase Fgr, Tyrosine-protein kinase Fgr
背景说明: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Swiss Prot: P09769
Gene ID: 2268
亚细胞定位: Cell membrane Cell projection Cytoplasm Cytoplasmic side Lipid-anchor Mitochondrion inner membrane Mitochondrion intermembrane space Peripheral membrane protein cytoskeleton cytosol ruffle membrane
免疫原: A synthetic peptide of human FGR
Public Immunogen Range: 1-100aa
理论分子量: 59kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。