Recombin human DFFA protein,BR

产品属性 Product Attributes

基本信息

基因名: DFFA
别名: DFF 45，DFF1，DFF45，DFF45/DFFA，DFFA，ICAD，Inhibitor of CAD
全名: DNA fragmentation factor，45kDa，alpha polypeptide
英文名称: Recombinant human DFFA protein
中文名称: DNA裂解因子45,α多肽
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： O00273
Gene ID： 1676
交叉反应： Human Mouse
分子量： 37kDa
区间范围： 1-331aa
背景说明： Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development.The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units.DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits.DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis.DFF becomes activated when DFFA is cleaved by caspase-3.The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF.DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis.Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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注意事项 Considerations

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