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- Recombinant Human Serpin F1,BR
Recombinant Human Serpin F1,BR
Recombinant Human Serpin F1
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产品属性 Product Attributes
基本信息
别名: Pigment Epithelium-Derived Factor;PEDF;Cell Proliferation-Inducing Gene 35 Protein;EPC-1;Serpin F1;SERPINF1;PEDF规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状): Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件: The product is shipped at ambient temperature.
产品信息
背景说明: Serpin F1 is a secreted glycoprotein that belongs to the noninhibitory serpin.It has an alpha/beta core serine-protease inhibitor domain,three major beta-sheets,and ten alpha-helices.As protease inhibitors,serpins have an array of functions including regulating blood clotting,the complement pathway,extracellular matrix remodeling,and cell motility.They are also involved in activities that extend beyond their ability to inhibit proteases.For instance,they may also regulate blood pressure,angiogenesis,or act as storage/transport proteins.Serpin F1 is a new promising approach for the treatment of osteosarcoma and has been described as a natural angiogenesis inhibitor with neurotrophic and immune-modulation properties.The human serpin superfamily consists of at least 35 members that target not only serine proteases,but also selected cysteine proteases and non-protease proteins.Levels of the natural ocular anti-angiogenic factor SentrinF1 (PEDF) is associated with proliferative retinopathy.来源: Human cells
其它标识
溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.内毒素: Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.
产品介绍 Product Introduction
Recombinant Human Serine Protease Inhibitor-clade F1 is produced by our Mammalian expression system and the target gene encoding Gln20-Pro418 is expressed with a 6His tag at the C-terminus.注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。