犬瘦素Elisa试剂盒,BR

产品属性 Product Attributes

基本信息

中文名称： 犬瘦素检测试剂盒
英文名称： Canine Leptin ELISA Kit
别名： FLJ94114; LEP; leptin (murine obesity homolog); leptin (obesity homolog, mouse); Leptin; OB; Obese protein; obese, mouse, homolog of; Obesity factor; OBOBS
储存条件： 2-8℃，6 months
规格： 48T ; 96T
检测目标： Leptin
样品类型： 血清/血浆/细胞培养上清
反应性： Canine
应用： ELISA
定量/定性： 定量检测
检测范围： 25-1600pg/mL
灵敏度： 5pg/mL
精密度： 板内，板间变异系数均<10%
回收率： 80%-120%

Elisa信息

Swiss Prot： O02720
Gene ID： 403616
背景说明： Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin and adiponectin protein of 30 kDa. Adiponectin is a circulating protein that is secreted exclusively by differentiated adipocytes. During adipocyte differentiation, mRNA levels of Adiponectin have been shown to be induced over 100-fold. Studies indicate that Adiponectin enhances the ability of sub-physiological levels of insulin to suppress glucose production, thus linking adipose tissue to whole body glucose regulation. Adiponectin function appears to be regulated by phosphatidylinositol-3-kinase (PI3-K) since Adiponectin secretion is blocked by pharmacologic inhibitors of this kinase. mRNA levels of Adiponectin have been shown to be significantly reduced in adipose tissue of obese patients with Type 2 diabetes relative to control subjects. Structural similarities to TNFalpha suggests that Adiponectin may play a role in pathogenesis of insulin resistance in Type 2 diabetes. Because Adiponectin is down-regulated in various forms of obesity and its structural similarity to TNFalpha, it is currently being investigated as an important regulator of whole body energy homeostasis.

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