小鼠骨形态发生蛋白3检测试剂盒,BR

产品属性 Product Attributes

基本信息

中文名称： 小鼠骨形态发生蛋白3检测试剂盒
英文名称： Mouse BMP3 ELISA Kit
别名： BMP3; BMP-3; BMP3A; BMP-3A; bone morphogenetic protein 3 (osteogenic); bone morphogenetic protein 3; Bone morphogenetic protein 3A; bone morphogenetic protein-3; Osteogenin
储存条件： 2-8℃，6 months
规格： 96T ; 48T
检测目标： BMP3
样品类型： 血清/血浆/细胞培养上清
反应性： Mouse
应用： ELISA
定量/定性： 定量检测
检测范围： 18.75-1200pg/mL
灵敏度： 9.375pg/mL
精密度： 板内，板间变异系数均<10%
回收率： 80%-120%
反应时间： 3h15min

Elisa信息

Swiss Prot： Q8BHE5
Gene ID： 110075
背景说明： Bone morphogenetic protein 3 (BMP3) is a protein in Mouses that is encoded by the BMP3 gene.[1] The protein encoded by this gene is a member of the transforming growth factor beta superfamily. It, like other bone morphogenetic proteins (BMP's) is known for its ability to induce bone and cartilage development. It is a disulfide-linked homodimer. It negatively regulates bone density.[2] BMP3 is an antagonist to other BMP's in the differentiation of osteogenic progenitors.BMP3 suppresses osteoblast differentiation of bone marrow stromal cells via interaction with activin receptor type 2b.[3] It is highly expressed in fractured tissues.[4] BMP3 is downregulated in cholangiocarcinoma (CC) and may act as a biomarker of the cancer.[5] Furthermore, promotor region methylation of the BMP3 gene may cause gastric carcinoma.[6]

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