Anti-HDAC4 Monoclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-HDAC4 Monoclonal Antibody
规格： 100ul ; 50ul
宿主： Mouse
克隆类型： Monoclonal Antibody
亚型： IgG2a克隆号 4A3-H7-C6
交叉反应：： Monkey ; Rat ; Mouse ; Human
应用： IP ; WB
稀释比例： WB 1:500-1000. IP 1:20.

抗体信息

靶标： HDAC4
别名： AHO3;BDMR;HA6116;HD4;HDAC-4;HDAC-A;HDACA
背景说明： Chromatin is a highly specialized structure composed of tightly compacted chromosomal DNA. Gene expression within the nucleus is controlled, in part, by a host of protein complexes which continuously pack and unpack the chromosomal DNA. One of the known mechanisms of this packing and unpacking process involves the acetylation and deacetylation of the histone proteins comprising the nucleosomal core. Acetylated histone proteins confer accessibility of the DNA template to the transcriptional machinery for expression. Histone deacetylases (HDACs) are chromatin remodeling factors that deacetylate histone proteins and thus, may act as transcriptional repressors. HDACs are classified by their sequence homology to the yeast HDACs and there are currently 2 classes. Class I proteins are related to Rpd3 and members of class II resemble Hda1p.HDAC4 is a class II histone deacetylase containing 1084 amino acid residues.
Swiss Prot： P56524
Gene ID： 9759
亚细胞定位： Cytoplasm Nucleus
免疫原： Recombinant protein of human HDAC4
理论分子量： 119kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，0.5% BSA，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。