Anti-SMAD5 Monoclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-SMAD5 Monoclonal Antibody
中文名称： 细胞信号转导分子SMAD5
规格： 100ul ; 50ul
宿主： Mouse
克隆类型： Monoclonal Antibody
亚型： IgG1克隆号 4B10-B10-B6
交叉反应：： Human
应用： IF ; FCM ; ICC ; WB
稀释比例： WB 1:500-1000. IF 1:50-200. FCM 1:50-100. ICC 1:50-200.

抗体信息

靶标： SMAD5
别名： Dwfc, hSmad 5, hSmad5, JV5 1, JV5-1, MAD homolog 5, MAD mothers against decapentaplegic homolog 5, MAD, mothers against decapentaplegic homolog 5, MADH 5, MADH5, Mothers against decapentaplegic homolog 5, Mothers against DPP homolog 5, MusMLP, SMA and MAD related protein 5, SMAD 5, SMAD family member 5, SMAD mothers against DPP homolog 5, Smad5, SMAD5_HUMAN
背景说明： SMAD5 is a member of the Mothers Against Dpp (MAD)-related family of proteins. It is a receptor-regulated SMAD (R-SMAD), and acts as an intracellular signal transducer for the transforming growth factor beta superfamily. SMAD5 is activated through serine phosphorylation by BMP (bone morphogenetic proteins) type 1 receptor kinase. It is cytoplasmic in the absence of its ligand and migrates into the nucleus upon phosphorylation and complex formation with SMAD4. Here the SMAD5/SMAD4 complex stimulates the transcription of target genes.
Swiss Prot： Q99717
Gene ID： 4090
亚细胞定位： Cytoplasm Nucleus
免疫原： Recombinant protein of human SMAD5
理论分子量： 52kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，0.5% BSA，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。