Anti-hnRNP U Monoclonal Antibody,BR

产品属性  Product Attributes

基本信息

英文名称：Anti-hnRNP U Monoclonal Antibody

中文名称：异质核糖核蛋白U抗体

规格：100ul ; 50ul

宿主：Mouse

克隆类型：Monoclonal Antibody

亚型：IgG1

克隆号：1B11-H2-B7

交叉反应：Human

应用：WB

稀释比例：WB 1:500-1000.

抗体信息

靶标：hnRNP U

别名：EIEE54;hnRNPU;HNRNPU-AS1;HNRPU;pp120;SAF-A;SAFA;U21.1;hnRNPU;HNRNPU-AS1;HNRPU;SAF-A;SAFA;U21.1

背景说明：This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they form complexes with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene contains a RNA binding domain and scaffold-associated region (SAR)-specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. Cleavage occurs at the SALD site, resulting in a loss of DNA-binding activity and a concomitant detachment of this protein from nuclear structural sites. But this cleavage does not affect the function of the encoded protein in RNA metabolism. At least two alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008]

Swiss Prot：Q00839

Gene ID：3192

亚细胞定位：Cell surface Cytoplasm Nucleus

免疫原：Recombinant protein of human hnRNP U

理论分子量：110kDa

其它标识

纯化方法：Affinity purification

储存液：PBS with 0.02% sodium azide，0.5% BSA，50% glycerol，pH7.3.

储存条件：Store at -20℃. Avoid freeze / thaw cycles.

产品介绍  Product Introduction

使用前请离心。如有问题请及时联系我们。

Quick spin before use. If you have any questions, please contact us.

注意事项  Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。