Anti-CKMT1 Monoclonal Antibody,BR

产品属性  Product Attributes

基本信息

英文名称：Anti-CKMT1 Monoclonal Antibody

中文名称：线粒体1B酸激酶抗体

规格：100ul ; 50ul

宿主：Mouse

克隆类型：Monoclonal Antibody

亚型：IgG1

克隆号：1A6-C7-G10

交叉反应：Mouse ; Human

应用：WB

稀释比例：WB 1:500-1000.

抗体信息

靶标：CKMT1

别名：Acidic type mitochondrial creatine kinase, CKMT, CKMT1, CKMT1A, CKMT1B, Creatine kinase mitochondrial 1 ubiquitous, Creatine kinase ubiquitous mitochondrial, Mia CK, Ubiquitous mitochondrial creatine kinase, UMTCK, KCRU_HUMAN

背景说明：Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.

Swiss Prot：P12532

Gene ID：548596

亚细胞定位：Intermembrane side Mitochondrion inner membrane Peripheral membrane protein

免疫原：Recombinant protein of human CKMT1

理论分子量：47kDa

其它标识

纯化方法  Affinity purification

储存液：PBS with 0.02% sodium azide，0.5% BSA，50% glycerol，pH7.3.

储存条件：Store at -20℃. Avoid freeze / thaw cycles.

产品介绍  Product Introduction

使用前请离心。如有问题请及时联系我们。

Quick spin before use. If you have any questions, please contact us.

注意事项  Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。