Anti-TLR7 Monoclonal Antibody,BR

英文名称:Anti-TLR7 Monoclonal Antibody
别名:TLR7-like;toll-like receptor 7

交叉反应:Transfected
应用:WB
稀释比例:WB 1:1000.
蛋白分子量:121kDa
Gene ID:51284
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG1
免疫原:Purified recombinant human TLR7 protein fragments expressed in E.coli.
性状:液体
亚细胞定位:Cytoplasmic vesicle Endoplasmic reticulum membrane Endosome Lysosome Single-pass type I membrane protein phagosome
Swiss Prot:Q9NYK1
克隆号:3F11-2C9-D8
背景资料:The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
克隆类型:Monoclonal Antibody
规格:50ul, 100ul, 注意：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。