Anti-LMNA Monoclonal Antibody,BR

产品属性  Product Attributes

基本信息

英文名称：Anti-LMNA Monoclonal Antibody

中文名称：层粘连蛋白A/C抗体

规格：100ul ; 50ul

宿主：Mouse

克隆类型：Monoclonal Antibody

亚型：IgG1

克隆号：5D12-C6-E9

交叉反应：Human ; Rat ; Mouse

应用：ICC ; IF ; WB

稀释比例：WB 1:500-1000. IF 1:50-200. ICC 1:50-200.

抗体信息

靶标：LMNA

别名：CDCD1;CDDC;CMD1A;CMT2B1;EMD2;FPL;FPLD;FPLD2;HGPS;IDC;LDP1;LFP;LGMD1B;LMN1;LMNC;LMNL1;MADA;PRO1;Lamin A/C

背景说明：The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

Swiss Prot：P02545

Gene ID：4000

亚细胞定位：Nucleus Nucleus envelope Nucleus lamina Nucleus speckle nucleoplasm

免疫原：Recombinant protein of human LMNA

理论分子量：74/65/71/64/63/69kDa

其它标识

纯化方法：Affinity purification

储存液：PBS with 0.02% sodium azide，0.5% BSA，50% glycerol，pH7.3.

储存条件：Store at -20℃. Avoid freeze / thaw cycles.

产品介绍  Product Introduction

使用前请离心。如有问题请及时联系我们。

Quick spin before use. If you have any questions, please contact us.

注意事项  Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。