Anti-Cleaved PARP Monoclonal Antibody,BR

Anti-Cleaved PARP Monoclonal Antibody

(订货以英文名为准)

产品编号：AC50212 品牌：Acmec

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中文名称：

Anti-Cleaved PARP Monoclonal Antibody

英文名称：

Anti-Cleaved PARP Monoclonal Antibody

保存条件：

-20℃

产品属性 Product Attributes

基本信息

英文名称：Anti-Cleaved PARP Monoclonal Antibody

中文名称：多腺苷二磷酸多聚酶/多聚ADP-核糖聚合酶1抗体

规格：100ul ; 50ul

宿主：Mouse

克隆类型：Monoclonal Antibody

亚型：IgG1

克隆号：Mix

交叉反应：Human

应用：WB ; IHC

稀释比例：WB 1:2000-5000. IHC 1:200-500.

抗体信息

靶标：Cleaved PARP

别名：ADPRT,ADPRT 1,ADPRT1,ARTD1,PARP,PARP-1,PPOL,pADPRT-1,poly(ADP-ribose) polymerase 1

背景说明：Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate.

Swiss Prot：P09874

Gene ID：142

亚细胞定位：Nucleus nucleolus

免疫原：Synthetic Peptide

理论分子量：116/89kDa

其它标识

纯化方法：Saturated ammonium sulfate precipitation

储存液：PBS with 0.02% sodium azide，50% glycerol，pH7.3.

储存条件：Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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