Anti-STAT3 Monoclonal Antibody,BR

产品属性  Product Attributes

基本信息

英文名称：Anti-STAT3 Monoclonal Antibody

中文名称：信号传导与转录激活因子3抗体

规格：100ul ; 50ul

宿主：Mouse

克隆类型：Monoclonal Antibody

亚型：IgG1

克隆号：3F4

交叉反应：Mouse ; Rat ; Human

应用：WB ; IHC

稀释比例：WB 1:1000-2000. IHC 1:100-200.

抗体信息

靶标：STAT3

别名：ADMIO;ADMIO1;APRF;HIES;ADMIO;APRF;HIES

背景说明：Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene . May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Involved in cell cycle regulation by inducing the expression of key genes for the progression from G1 to S phase, such as CCND1. Mediates the effects of LEP on melanocortin production, body energy homeostasis and lactation (By similarity). May play an apoptotic role by transctivating BIRC5 expression under LEP activation . Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity.

Swiss Prot：P40763

Gene ID：6774

亚细胞定位：Cytoplasm Nucleus

免疫原：Recombinant Protein

理论分子量：83/88kDa

其它标识

纯化方法：Saturated ammonium sulfate precipitation

储存液：PBS with 0.02% sodium azide，50% glycerol，pH7.3.

储存条件：Store at -20℃. Avoid freeze/thaw cycles.

产品介绍  Product Introduction

使用前请离心。如有问题请及时联系我们。

Quick spin before use. If you have any questions, please contact us.

注意事项  Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。