Anti-RAF1 Polyclonal Antibody,BR

产品属性  Product Attributes

基本信息

英文名称：Anti-RAF1 Polyclonal Antibody

中文名称：小鼠白血病病毒癌基因同源物v-raf-1抗体

规格：100ul ; 50ul

宿主：Rabbit

克隆类型：Polyclonal Antibody

亚型：IgG

交叉反应：Mouse ; Rat ; Human

应用：IHC ; WB ; IF ; ELISA

稀释比例：WB 1:500-1000. IHC 1:50-200. IF 1:50-200.

抗体信息

靶标：RAF1

别名：c Raf, CRAF, NS5, Proto oncogene c RAF, RAF, Raf 1, RAF1

背景说明：This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.

Swiss Prot：P04049

Gene ID：5894

亚细胞定位：Cell membrane Cytoplasm Mitochondrion Nucleus

免疫原：Recombinant protein of human RAF1

Public Immunogen Range：190-350aa

理论分子量：73kDa

其它标识

纯化方法  Affinity purification

储存液：PBS with 0.02% sodium azide，50% glycerol，pH7.3.

储存条件：Store at -20℃. Avoid freeze/thaw cycles.

产品介绍  Product Introduction

使用前请离心。如有问题请及时联系我们。

Quick spin before use. If you have any questions, please contact us.

注意事项  Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。