Anti-CDK4 Polyclonal Antibody,BR

产品属性  Product Attributes

基本信息

英文名称：Anti-CDK4 Polyclonal Antibody

中文名称：周期蛋白-依赖性蛋白激酶4抗体

规格：100ul ; 50ul

宿主：Rabbit

克隆类型：Polyclonal Antibody

亚型：IgG

交叉反应：Mouse ; Human

应用：IF ; WB ; IP ; ELISA

稀释比例：WB 1:500-1000. IF 1:50-200. IP 0.5μg-4μg.

抗体信息

靶标：CDK4

别名：Cdk 4,CDK4 protein,Cell division kinase 4,Cell division protein kinase 4,CMM 3,CMM3,Crk3,Cyclin dependent kinase 4,Melanoma cutaneous malignant 3,MGC14458,p34 cdk4,PSK J3,CDK4_HUMAN

背景说明：The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.

Swiss Prot：P11802

Gene ID：1019

亚细胞定位：Cytoplasm Membrane Nucleus

免疫原：A synthetic peptide of human CDK4

Public Immunogen Range：200-303aa

理论分子量：34kDa

其它标识

纯化方法：Affinity purification

储存液：PBS with 0.02% sodium azide，50% glycerol，pH7.3.

储存条件：Store at -20℃. Avoid freeze/thaw cycles.

产品介绍  Product Introduction

使用前请离心。如有问题请及时联系我们。

Quick spin before use. If you have any questions, please contact us.

注意事项  Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。