Anti-UPF1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-UPF1 Polyclonal Antibody
中文名称： ATP依赖解旋酶RENT1抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human
应用： IP ; IF ; WB
稀释比例： WB 1:500-2000. IF 1:50-200. IP 0.5μg-4μg.

抗体信息

靶标： UPF1
别名： ATP dependent helicase RENT1, ATP-dependent helicase RENT1, Delta helicase, HUPF 1, HUPF1, KIAA0221, Nonsense mRNA reducing factor 1, NORF 1, NORF1, pNORF 1, pNORF1, Regulator of nonsense transcripts 1, RENT 1, RENT1, RENT1_HUMAN, Smg 2, Smg 2 homolog nonsense mediated mRNA decay factor, UP Frameshift 1, Up frameshift mutation 1 homolog (S. cerevisiae), Up frameshift mutation 1 homolog, Up frameshift suppressor 1 homolog, Up-frameshift mutation 1 homolog (S. cerevisiae), Up-frameshift suppressor 1 homolog, UPF 1, UPF 1 regulator of nonsense transcripts homolog, UPF1
背景说明： This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.
Swiss Prot： Q92900
Gene ID： 5976
亚细胞定位： Cytoplasm Nucleus P-body
免疫原： Recombinant protein of human UPF1
Public Immunogen Range： 819-1118aa
理论分子量： 124kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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