Anti-EIF4G2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-EIF4G2 Polyclonal Antibody
中文名称： 死亡相关蛋白5抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IP ; IF ; IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-200. IF 1:50-200. IP 0.5μg-4μg.

抗体信息

靶标： EIF4G2
别名： eIF-4-gamma 2,eIF-4G 2,eIF4G 2,Death-associated protein 5,DAP-5,p97,DAP5,OK/SW-cl.75
背景说明： Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Swiss Prot： P78344
Gene ID： 1982
亚细胞定位： Cytosol
免疫原： Recombinant protein of human EIF4G2
Public Immunogen Range： 320-490aa
理论分子量： 102kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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