Anti-ERCC1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ERCC1 Polyclonal Antibody
中文名称： DNA切除修复蛋白1抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse ; Rat
应用： WB
稀释比例： WB 1:500-1000.

抗体信息

靶标： ERCC1
别名： Excision Repair Cross Complementing 1, DNA excision repair protein ERCC-1, COFS4, UV20, DNA excision repair protein ERCC1, ERCC 1, Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1, Excision repair protein, UV 20, UV20,DNA excision repair protein ERCC-1
背景说明： The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand.
Swiss Prot： P07992
Gene ID： 2067
亚细胞定位： Cytoplasm Nucleus
免疫原： Recombinant protein of human ERCC1
Public Immunogen Range： 1-323aa
理论分子量： 33kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。