Anti-MBNL1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-MBNL1 Polyclonal Antibody
中文名称： MBNL1蛋白抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human ; Rat
应用： IF ; WB ; IHC
稀释比例： WB 1:500-2000. IHC 1:50-200. IF 1:50-100.

抗体信息

靶标： MBNL1
别名： Muscleblind-like 1,EXP, EXP35, EXP40, EXP42, KIAA0428, MBNL, MBNL protein, MBNL1, MBNL1_HUMAN, Muscleblind 41kD isoform, Muscleblind like, Muscleblind like protein 1, Muscleblind like splicing regulator 1, Muscleblind-like protein 1, Triplet expansion RNA binding protein, Triplet-expansion RNA-binding protein
背景说明： This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.
Swiss Prot： Q9NR56
Gene ID： 4154
亚细胞定位： Cytoplasm Cytoplasmic granule Nucleus
免疫原： Recombinant protein of human MBNL1
Public Immunogen Range： 1-382aa
理论分子量： 42kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。