Anti-SMC1A(N-term) Monoclonal Antibody,BR

英文名称:Anti-SMC1A(N-term) Monoclonal Antibody
宿主:Mouse
别名:CDLS2;DXS423E;SB1.8;SMC1;SMC1alpha;SMC1L1;SMCB
交叉反应:Human
应用:WB IHC FC
稀释比例:WB 1:1000.
蛋白分子量:143kDa
Gene ID:8243
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG1
免疫原:Purified recombinant human SMC1A(N-terminus) protein fragments expressed in E.coli.
性状:液体
亚细胞定位:Chromosome Nucleus centromere kinetochore
Swiss Prot:Q14683
克隆号:8E6-A4-F3
背景资料:

Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation.
Public Immunogen Range:Purified recombinant human SMC1A(N-terminus) protein fragments expressed in E.coli.
克隆类型:Monoclonal Antibody
规格:50ul, 100ul,

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