Anti-SMC1A Monoclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-SMC1A Monoclonal Antibody
中文名称： 染色体结构维持蛋白质1抗体
规格： 100ul ; 50ul
宿主： Mouse
克隆类型： Monoclonal Antibody
亚型： IgG1克隆号 4C5-C8-A11
交叉反应：： Human
应用： IF ; ICC ; WB
稀释比例： WB 1:500-1000. IF 1:50-200. ICC 1:50-200.

抗体信息

靶标： SMC1A
别名： CDLS2;DXS423E;SB1.8;SMC1;SMC1alpha;SMC1L1;SMCB
背景说明： Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. [provided by RefSeq, Jul 2008]
Swiss Prot： Q14683
Gene ID： 8243
亚细胞定位： Chromosome Nucleus centromere kinetochore
免疫原： Recombinant protein of human SMC1A
理论分子量： 143kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，0.5% BSA，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。