Anti-PDHA1 Monoclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PDHA1 Monoclonal Antibody
中文名称： 丙酮酸脱氢酶α1抗体
规格： 100ul ; 50ul
宿主： Mouse
克隆类型： Monoclonal Antibody
亚型： IgG1克隆号 3H2-F8-B5
交叉反应：： Mouse ; Human
应用： IF ; ICC ; WB
稀释比例： WB 1:500-1000. IF 1:50-200. ICC 1:50-200.

抗体信息

靶标： PDHA1
别名： PDHA;PDHAD;PDHCE1A;PHE1A
背景说明： The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： P08559
Gene ID： 5160
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human PDHA1
理论分子量： 43kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，0.5% BSA，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。