Anti-Jak1 Monoclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-Jak1 Monoclonal Antibody
中文名称： Janus激酶1,酪氨酸蛋白激酶1抗体
规格： 100ul ; 50ul
宿主： Mouse
克隆类型： Monoclonal Antibody
亚型： IgG2a克隆号 8B8-E7-G3
交叉反应：： Rat ; Human
应用： ICC ; IP ; IF ; WB
稀释比例： WB 1:500-1000. IF 1:50-200. IP 1:20. ICC 1:50-200.

抗体信息

靶标： Jak1
别名： JAK1A;JAK1B;JTK3;Janus kinase 1
背景说明： Janus kinase 1 (JAK1), is a member of a new class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. JAK1 is involved in the interferon-alpha/beta and -gamma signal transduction pathways. The reciprocal interdependence between JAK1 and TYK2 activities in the interferon-alpha pathway, and between JAK1 and JAK2 in the interferon-gamma pathway, may reflect a requirement for these kinases in the correct assembly of interferon receptor complexes. These kinases couple cytokine ligand binding to tyrosine phosphorylation of various known signaling proteins and of a unique family of transcription factors termed the signal transducers and activators of transcription, or STATs.
Swiss Prot： P23458
Gene ID： 3716
亚细胞定位： Endomembrane system Peripheral membrane protein
免疫原： Recombinant protein of human Jak1
理论分子量： 133kDa

其它标识

纯化方法： Saturated ammonium sulfate precipitation
储存液： PBS with 0.02% sodium azide，0.5% BSA，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。