Anti-FADD Monoclonal Antibody,BR
Anti-FADD Monoclonal Antibody
(订货以英文名为准)
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英文名称:Anti-FADD Monoclonal Antibody
宿主:Mouse
别名:GIG3;MORT1
交叉反应:Human
应用:WB
稀释比例:WB 1:500.
蛋白分子量:23kDa
Gene ID:8772
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG2a
免疫原:Recombinant human FADD protein.
性状:液体
亚细胞定位:Cytosol Nucleus Plasma Membrane
Swiss Prot:Q13158
克隆号:5A3-C7-G9
背景资料:
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals.Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor,tumor necrosis factor receptor,TNFRSF25,and TNFSF10/TRAIL-receptor,and thus it participates in the death signaling initiated by these receptors.Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein,which allows it to recruit caspase-8,and thereby activate the cysteine protease cascade.Knockout studies in mice also suggest the importance of this protein in early T cell development.[provided by RefSeq,Jul 2008]
Public Immunogen Range:Recombinant human FADD protein.
克隆类型:Monoclonal Antibody
规格:50ul, 100ul,
注意：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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