Anti-MAPK8 Monoclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-MAPK8 Monoclonal Antibody
中文名称： 磷酸化氨基末端激酶1/2/3抗体
规格： 100ul ; 50ul
宿主： Mouse
克隆类型： Monoclonal Antibody
亚型： IgG2a克隆号 1A4-C5-F11
交叉反应：： Mouse ; Rat ; Human
应用： ICC ; IF ; WB
稀释比例： WB 1:500-1000. IF 1:50-200. ICC 1:50-200.

抗体信息

靶标： MAPK8
别名： JNK;JNK-46;JNK1;JNK1A2;JNK21B1/2;PRKM8;SAPK1;SAPK1c
背景说明： The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
Swiss Prot： P45983
Gene ID： 5599
亚细胞定位： Cytoplasm Nucleus
免疫原： Recombinant protein of human MAPK8
理论分子量： 48kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，0.5% BSA，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。