Anti-Phospho-NFκB p105-S927 Polyclonal Antibody,BR

英文名称:Anti-Phospho-NFκB p105-S927 Polyclonal Antibody
宿主:Rabbit
别名:CVID12;EBP-1;KBF1;NF-kB1;NF-kappa-B;NF-kappaB;NFKB-p105;NFKB-p50;NFkappaB;p105;p50
交叉反应:Human
应用:WB
稀释比例:WB 1:500-1000.
蛋白分子量:86/105kDa
Gene ID:4790
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:A phospho specific peptide corresponding to residues surrounding S927 of human NFκB p105
亚细胞定位:Cytoplasm Nucleus
Swiss Prot:P19838
背景资料:

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.
克隆类型:Polyclonal Antibody
规格:50ul, 100ul,

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