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Anti-TRAF3 Monoclonal Antibody,BR
Anti-TRAF3 Monoclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-TRAF3 Monoclonal Antibody中文名称: 肿瘤坏死因子受体相关蛋白3抗体
规格: 50ul ; 100ul
宿主: Mouse
亚型: IgG2a
交叉反应: Human
应用: WB ; IHC ; IF/ICC ; ELISA
稀释比例: WB 1:500-2000. IHC 1:200-800. IF/ICC 1:200-800.
抗体信息
靶标: TRAF3别名: CAP-1;CAP1;CD40bp;CRAF1;IIAE5;LAP1
背景说明: TNF receptor-associated factor 3 (TRAF3) has many alternative names including CAP-1 CD40 receptor-associated factor 1(CRAF1) CD40-binding protein(CD40BP) and LMP1-associated protein 1 (LAP1). TRAF3 regulates pathways leading to the activation of NF-kappa-B and MAP kinases and plays a central role in the regulation of innate immune response. It modulates signaling pathways leading to the production of cytokines and interferon. As an essential constituent of several E3 ubiquitin-protein ligase complexes TRAF3 promote 'Lys-63'-linked ubiquitination of target proteins. Moreover TRAF3 undergoes both 'Lys-48'-linked and 'Lys-63'-linked ubiquitination in response to various stimuli and is deubiquitinated by OTUB1 OTUB2 and OTUD5.
Swiss Prot: Q13114
Gene ID: 7187
亚细胞定位: Cytoplasm Endosome Mitochondrion
研究领域: 细胞生物学 ; 发育生物学
免疫原: Recombinant protein of human TRAF3 Public Immunogen Range 6-351aa
理论分子量: 55/64kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
运输条件: 冷冻运输
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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