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Anti-BCL2L1 Polyclonal Antibody,BR
Anti-BCL2L1 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-BCL2L1 Polyclonal Antibody中文名称: Bcl-xL蛋白抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Rat
应用: IF ; IHC ; WB
稀释比例: WB 1:500-1000. IHC 1:50-200. IF 1:50-200.
抗体信息
靶标: BCL2L1别名: BCL-XL/S;BCL2L;BCLX;Bcl-X;PPP1R52
背景说明: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
Swiss Prot: Q07817
Gene ID: 598
亚细胞定位: Cytoplasm Cytoplasmic side Cytoplasmic vesicle Mitochondrion inner membrane Mitochondrion matrix Mitochondrion outer membrane Nucleus membrane Single-pass membrane protein centrosome cytoskeleton cytosol microtubule organizing center secretory vesicle synaptic vesicle membrane
免疫原: Recombinant protein of human BCL2L1
Public Immunogen Range: 1-80aa
理论分子量: 26kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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