Anti-CASP12 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CASP12 Polyclonal Antibody
中文名称： 半胱胺酸蛋白酶蛋白-12抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human
应用： IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-200.

抗体信息

靶标： CASP12
别名： UNQ9415, Apoptosis related cysteine protease, CASP 12, casp12, CASP12P1, Caspase 12 pseudogene 1, CASP-12, casp12, caspase 12 (gene/pseudogene), Caspase12, CASPC_HUMAN,
背景说明： Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene.
Swiss Prot： Q6UXS9
Gene ID： 100506742
亚细胞定位： Endoplasmic reticulum
免疫原： A synthetic peptide of human CASP12
Public Immunogen Range： 200-300aa
理论分子量： 19/29/39kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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