Anti-CD40 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CD40 Polyclonal Antibody
中文名称： 肿瘤坏死因子受体超家族成员5抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应： Mouse ; Human
应用： WB ; IHC-P ; IF/ICC ; ELISA
稀释比例： WB 1:500-1000. IHC-P 1:50-200. IF/ICC 1:50-200.

抗体信息

靶标： CD40
别名： Tumor necrosis factor receptor superfamily , member 5,B cell associated molecule CD40,B cell surface antigen CD40,B cell-associated molecule,B-cell surface antigen CD40,Bp50,CD 40,CD40,CD40 antigen (TNF receptor superfamily member 5),CD40 antigen,CD40 molecule,CD40 molecule, TNF receptor superfamily member 5,CD40 protein,CD40 type II isoform
背景说明： This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Swiss Prot： P25942
Gene ID： 958
亚细胞定位： Cell membrane Secreted Single-pass type I membrane protein
研究领域： 免疫学 ; 心血管
免疫原： Recombinant Protein of human CD40Public Immunogen Range 198-277aa
理论分子量： 31kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.
运输条件： 冷冻运输

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。