Anti-MAPK14 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-MAPK14 Polyclonal Antibody
中文名称： 丝裂原活化蛋白激酶14抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse ; Rat
应用： IHC ; WB
稀释比例： WB 1:100-500. IHC 1:50-200.

抗体信息

靶标： MAPK14
别名： MAPK14;CSBP;CSBP1;CSBP2;CSPB1;EXIP;Mxi2;PRKM14;PRKM15;RK;SAPK2A;p38;p38ALPHA;mitogen-activated protein kinase 14
背景说明： The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Swiss Prot： Q16539
Gene ID： 1432
亚细胞定位： Cytoplasm Nucleus
免疫原： A synthetic peptide of human MAPK14
Public Immunogen Range： 261-360aa
理论分子量： 29/34/35/41kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.03% Proclin300，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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