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- Anti-MAP2K2 Polyclonal Antibody,BR
Anti-MAP2K2 Polyclonal Antibody,BR
Anti-MAP2K2 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-MAP2K2 Polyclonal Antibody中文名称: 丝裂原活化蛋白激酶2抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Mouse
应用: WB
稀释比例: WB 1:500-2000
抗体信息
靶标: MAP2K2别名: CFC4;MAPKK2;MEK2;MKK2;PRKMK2
背景说明: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.
Swiss Prot: P36507
Gene ID: 5605
亚细胞定位: Cytoplasm Membrane Peripheral membrane protein
免疫原: A synthetic peptide of human MAP2K2
Public Immunogen Range: 1-100aa
理论分子量: 44kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。