Anti-ABL1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ABL1 Polyclonal Antibody
中文名称： 磷酸化非受体酪氨酸激酶c-Abl抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse ; Rat
应用： IF ; IHC ; WB
稀释比例： WB 1:100-500. IHC 1:50-200. IF 1:50-200.

抗体信息

靶标： ABL1
别名： Abelson murine leukemia viral oncogene homolog 1,Abelson tyrosine protein kinase 1,Abl 1,ABL,ABL proto oncogene 1 non receptor tyrosine kinase,ABL1,ABL1_HUMAN,bcr/abl,bcr/c abl oncogene protein,c ABL,c abl oncogene 1 non receptor tyrosine kinase,c abl oncogene 1 receptor tyrosine kinase,c ABL1,JTK7,p150,Proto oncogene tyrosine protein kinase ABL1,Proto-oncogene c-Abl
背景说明： This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.
Swiss Prot： P00519
Gene ID： 25
亚细胞定位： Cytoplasm Lipid-anchor Mitochondrion Nucleus Nucleus membrane cytoskeleton
免疫原： Recombinant protein of human ABL1
Public Immunogen Range： 1000-1130aa
理论分子量： 123kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

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2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。