Anti-PKN1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PKN1 Polyclonal Antibody
中文名称： 蛋白激酶C相关激酶1抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse
应用： WB
稀释比例： WB 1:500-1000

抗体信息

靶标： PKN1
别名： DBK;PAK-1;PAK1;PKN;PKN-ALPHA;PRK1;PRKCL1
背景说明： The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Swiss Prot： Q16512
Gene ID： 5585
亚细胞定位： Cell membrane Cleavage furrow Cytoplasm Endosome Midbody Nucleus Peripheral membrane protein
免疫原： Recombinant protein of human PKN1
Public Immunogen Range： 1-300aa
理论分子量： 104kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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