Anti-NOTCH2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-NOTCH2 Polyclonal Antibody
中文名称： 跨膜受体蛋白Notch-2抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse
应用： IF ; WB
稀释比例： WB 1:500-2000.IF 1:50-200

抗体信息

靶标： NOTCH2
别名： Activated Notch 2,Notch2,hN2,Notch 2 extracellular truncation,Notch 2 intracellular domain,AGS2,hN2,Motch B
背景说明： This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： Q04721
Gene ID： 4853
亚细胞定位： Cell membrane Cytoplasm Nucleus Single-pass type I membrane protein
免疫原： Recombinant protein of human NOTCH2
Public Immunogen Range： 2242-2471aa
理论分子量： 265kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。