Anti-INCENP Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-INCENP Polyclonal Antibody
中文名称： 内着丝粒蛋白抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Human
应用： WB
稀释比例： WB 1:500-2000.

抗体信息

靶标： INCENP
别名： binds and activates aurora B and C in vivo and in vitro, Chromosomal passenger protein, FLJ31633, INCE_HUMAN, INCENP, Inner centromere protein, Inner centromere protein antigens 135/155kDa, Inner centromere protein antigens 135kD 155kD, Inner centromere protein INCENP, MGC111393
背景说明： In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (centromere protein A; MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142). The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994 [PubMed 8088460]). These include CENPE (MIM 117143); MCAK (MIM 604538); KID (MIM 603213); cytoplasmic dynein (e.g., MIM 600112); CliPs (e.g., MIM 179838); and CENPF/mitosin (MIM 600236). The inner centromere proteins (INCENPs) (Earnshaw and Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis (Cutts et al., 1999 [PubMed 10369859]).
Swiss Prot： Q9NQS7
Gene ID： 3619
亚细胞定位： Chromosome Cytoplasm Nucleus centromere cytoskeleton kinetochore spindle
免疫原： Recombinant protein of human INCENP
Public Immunogen Range： 785-914aa
理论分子量： 105kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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