Anti-CTSB Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CTSB Polyclonal Antibody
中文名称： 组织蛋白酶 B抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Human ; Mouse
应用： IF ; IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-200. IF 1:50-200.

抗体信息

靶标： CTSB
别名： Amyloid precursor protein secretase, APP secretase, APPS, Cathepsin B, CB, Cathepsin B1, CathepsinB, CPSB, CTSB, Cysteine protease, Preprocathepsin B, Cathepsin B heavy chain, Cathepsin B light chain, CATB_HUMAN
背景说明： This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. Multiple pseudogenes of this gene have been identified.
Swiss Prot： P07858
Gene ID： 1508
亚细胞定位： Lysosome Melanosome Secreted extracellular space
免疫原： Recombinant protein of human CTSB
Public Immunogen Range： 18-339aa
理论分子量： 38kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.03% Proclin300，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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