Anti-DSC1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-DSC1 Polyclonal Antibody
中文名称： 桥粒糖蛋白1抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： WB
稀释比例： WB 1:500-1000.

抗体信息

靶标： DSC1
别名： Cadherin family member 1, CDHF1, Desmocollin1, Desmosomal glycoprotein 2/3, DG2/DG3, DSC 1, DSC1, DSC1_HUMAN
背景说明： The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein.
Swiss Prot： Q08554
Gene ID： 1823
亚细胞定位： Cell junction Cell membrane Single-pass type I membrane protein desmosome
免疫原： Recombinant protein of human DSC1
Public Immunogen Range： 480-690aa
理论分子量： 100/94kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。