Anti-PDF Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PDF Polyclonal Antibody
中文名称： 肽脱甲酰基酶PDF抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： WB
稀释比例： WB 1:500-2000. IHC 1:50-200.

抗体信息

靶标： PDF
别名： PDF,CG6496, DEFM_HUMAN, mitochondrial, Pdf, PDF1A, Peptide deformylase, Peptide deformylase like protein, Peptide deformylase, mitochondrial, Polypeptide deformylase
背景说明： Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells.
Swiss Prot： Q9HBH1
Gene ID： 64146
亚细胞定位： Mitochondrion
免疫原： Recombinant protein of human PDF
Public Immunogen Range： 40-243aa
理论分子量： 27kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。