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- Anti-RASGRP1 Polyclonal Antibody,BR
Anti-RASGRP1 Polyclonal Antibody,BR
Anti-RASGRP1 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-RASGRP1 Polyclonal Antibody中文名称: Ras蛋白特异鸟嘌呤核苷酸释放因子1抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Rat ; Human ; Mouse
应用: IF ; WB
稀释比例: WB 1:500-1000. IF 1:50-200.
抗体信息
靶标: RASGRP1别名: CALDAG-GEFI;CALDAG-GEFII;RASGRP;V;hRasGRP1
背景说明: This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE).
Swiss Prot: O95267
Gene ID: 10125
亚细胞定位: Cell membrane Cytoplasm Endoplasmic reticulum membrane Golgi apparatus membrane Peripheral membrane protein cytosol
免疫原: Recombinant protein of human RASGRP1
Public Immunogen Range: 598-797aa
理论分子量: 90kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。