Anti-ABCA4 Polyclonal Antibody,BR

英文名称:Anti-ABCA4 Polyclonal Antibody
宿主:Rabbit
别名:ABC10;ABCR;ARMD2;CORD3;FFM;RMP;RP19;STGD;STGD1
交叉反应:Human Mouse Rat
应用:WB IF
稀释比例:WB 1:1000-2000. IF 1:50-200.
蛋白分子量:256kDa
Gene ID:24
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:Recombinant protein of human ABCA4
性状:液体
亚细胞定位:Membrane Multi-pass membrane protein
Swiss Prot:P78363
背景资料:

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.
Public Immunogen Range:Recombinant protein of human ABCA4
克隆类型:Polyclonal Antibody
规格:50ul, 100ul,

注意：
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