Anti-COL4A1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-COL4A1 Polyclonal Antibody
中文名称： IV型胶原蛋白/4型胶原蛋白/胶原蛋白4抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： WB
稀释比例： WB 1:500-2000

抗体信息

靶标： COL4A1
别名： Arresten,Canstatin,COL4A1,HANAC,ICH,POREN1,Collagen Alpha 1(IV) Chain,Collagen IV Alpha 1 Polypeptide,Collagen Of Basement Membrane Alpha 1 Chain,COL4A1 NC1 domain, Collagen Ⅳ, Collagen Type Ⅳ
背景说明： This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants.
Swiss Prot： P02462
Gene ID： 1282
亚细胞定位： Cytoplasm Basement membrane ExtraCellular space ExtraCellular matrix
免疫原： Recombinant protein of human COL4A1
Public Immunogen Range： 1445-1669aa
理论分子量： 161kDa/50kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.03% Proclin300，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。