Anti-MYH11 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-MYH11 Polyclonal Antibody
中文名称： 平滑肌肌球蛋白重链抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： IF ; WB
稀释比例： WB 1:100-500. IF 1:50-200.

抗体信息

靶标： MYH11
别名： SMMHC, Myosin 11, Myosin-11, Myosin, smooth muscle, heavy chain, Myosin Smooth Muscle, AAT 4, AAT4, DKFZp686D10126, DKFZp686D19237, FAA 4, FAA4, FLJ35232, KIAA0866, MGC126726, MGC32963, MYH 11, MYH11 protein, Myosin heavy chain 11 smooth muscle, Myosin heavy chain smooth muscle isoform, Myosin heavy polypeptide 11 smooth muscle, Myosin11, SMHC, Smooth muscle myosin heavy chain isoform SM1, MYH11_HUMAN
背景说明： The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Swiss Prot： P35749
Gene ID： 4629
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human MYH11
Public Immunogen Range： 1680-1979aa
理论分子量： 223/228kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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