Anti-AMBRA1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-AMBRA1 Polyclonal Antibody
中文名称： BECN1调节的自噬蛋白1中的激活分子抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： IHC ; WB ; IF
稀释比例： WB 1:500-1000. IHC 1:50-200. IF 1:50-200.

抗体信息

靶标： AMBRA1
别名： Activating molecule in beclin 1 regulated autophagy, Activating molecule in BECN1 regulated autophagy protein 1, Hypothetical protein FLJ20294, Hypothetical protein LOC55626, KIAA1736, MGC33725, WDR94, AMRA1_HUMAN
背景说明： WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. AMBRA1 (Activating molecule in BECN1-regulated autophagy protein 1), also known as WDR94 or KIAA1736, is a 1,298 amino acid protein that contains three WD repeats. Localized to cytoplasmic vesicles, AMBRA1 functions to control protein turnover, cell proliferation and cell survival during neuronal development, thereby playing an important role in autophagy and the development of the nervous system. Multiple isoforms of AMBRA1 exist due to alternative spicing events.
Swiss Prot： Q9C0C7
Gene ID： 55626
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human AMBRA1
Public Immunogen Range： 1109-1208aa
理论分子量： 143kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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