Anti-TNFRSF1B Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-TNFRSF1B Polyclonal Antibody
中文名称： 肿瘤坏死因子受体超家族, 成员1B抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human
应用： WB
稀释比例： WB 1:500-1000.

抗体信息

靶标： TNFRSF1B
别名： CD120b;TBPII;TNF-R-II;TNF-R75;TNFBR;TNFR1B;TNFR2;TNFR80;p75;p75TNFR
背景说明： The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Swiss Prot： P20333
Gene ID： 7133
亚细胞定位： Cell membrane Secreted Single-pass type I membrane protein
免疫原： A synthetic peptide of human TNFRSF1B
Public Immunogen Range： 295-377aa
理论分子量： 48kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。