Anti-APP Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-APP Polyclonal Antibody
中文名称： β-淀粉样蛋白(A4)前体蛋白抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human
应用： IF ; WB
稀释比例： WB 1:500-1000. IF 1:50-200.

抗体信息

靶标： APP
别名： AAA;ABETA;ABPP;AD1;APPI;CTFgamma;CVAP;PN-II;PN2
背景说明： This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
Swiss Prot： P05067
Gene ID： 351
亚细胞定位： Membrane Single-pass type I membrane protein clathrin-coated pit
免疫原： A synthetic peptide of human APP
Public Immunogen Range： 1-100aa
理论分子量： 87kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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