Anti-STAT3 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-STAT3 Polyclonal Antibody
中文名称： 信号传导与转录激活因子3抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Human ; Mouse
应用： IF ; WB
稀释比例： WB 1:500-2000.IF 1:50-200

抗体信息

靶标： STAT3
别名： ADMIO;ADMIO1;APRF;HIES;ADMIO;APRF;HIES
背景说明： The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Swiss Prot： P40763
Gene ID： 6774
亚细胞定位： Cytoplasm Nucleus
免疫原： A synthetic peptide of human STAT3
Public Immunogen Range： 600-700aa
理论分子量： 83/88kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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