Anti-CASP3 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CASP3 Polyclonal Antibody
中文名称： 胱天蛋白酶3抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： IF ; IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-200. IF 1:100-500.

抗体信息

靶标： CASP3
别名： CPP32;CPP32B;SCA-1;Caspase 3;SREBP cleavage activity 1;Cysteine protease CPP32
背景说明： This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Swiss Prot： P42574
Gene ID： 836
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human CASP3
Public Immunogen Range： 6-105aa
理论分子量： 32kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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